[Emblem of Prague]
Jan Hus

(asi 1371 - 6.7.1415)
Český reformátor, kazatel v Betlémské kapli (1402 - 1412). Mistr na pražské univerzitě. V roce 1870 na 4 000 Pražanů si vyžádalo, aby ulice byla zvána Husovou třídou.

The sign is on Husova Street, a street named after the theologian and one of the leaders of the Protestant Reformation, who in 1415 was burned at the stake due to his views.

The place where the sign is located was photographed on the same day by the same photographer Click for a larger image
(Note that the sign is in the same format as street signs in Prague Click for sign's details

Translation of the text on the sign:
Jan Hus

(about 1371 - 6.7.1415)
Czech reformer, preacher in the Bethlehem Chapel (1402 - 1412). Master at the University of Prague. In 1870, 4,000 Prague residents requested that the street be called Husová třída.